Bretylium Tosylate in the Treatment of Hypertension
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چکیده
منابع مشابه
Bretylium tosylate in prevention of cardiac dysrhythmias after myocardial infarction.
The prophylactic value of parenterally administered bretylium tosylate against the onset of dysrhythmias after acute myocardial infarction has been assessed by a controlled trial in 101 male patients. Bretylium significantly reduced the incidence of supraventricular dysrhythmias but was without significant effect on the incidence of ventricular dysrhythmias. The only serious side-effect of the ...
متن کاملPrevention of chronic canine ventricular tachyarrhythmias with bretylium tosylate.
The ability of chronic bretylium tosylate treatment to prevent the induction of ventricular tachycardia was assessed in the conscious dog subjected to serial programmed ventricular stimulation on days 3-6 after acute myocardial infarction. In 34 untreated control dogs, programmed ventricular stimulation produced nonsustained ventricular tachycardia in 11 dogs (32%), sustained ventricular tachyc...
متن کاملEvaluation of bretylium tosylate for the treatment of premature ventricular contractions.
In a controlled setting bretylium tosylate was evaluated for efficacy, toxicity, onset, and duration of action in eight patients with frequent premature ventricular contractions (PVC). Four patients received a single im dose of bretylium, 4 mg/kg, with before and after control days; the other four patients received bretylium, 2 and 4 mg/kg, on different days with before and between control days...
متن کاملEffect of bretylium tosylate (Darenthin) on pulmonary circulation.
BRETYLIUM tosylate (Darenthin, Burroughs Wellcome), is one of the series of benzyl quaternary ammonium compounds which blocks selectively the peripheral sympathetic nervous system without antagonizing the effects of epinephrine. This block occurs without depression of the parasympathetic or central nervous system.' Its effect on the pulmonary circulation has not hitherto been investigated. ,_ ....
متن کاملEffectiveness of bretylium tosylate against refractory ventricular arrhythmias.
Thirty patients with ventricular tachyarrhythmias, which had not responded to intensive therapy with up to five antiarrhythmic drugs, were treated with bretylium tosylate. All patients had recurrenit ventricular tachycardia, and 12 had repeated episodes of ventricular fibrillation. In 17 patients the arrhythmias followed acute myocardial infarction. Bretylium was administered intramuscularly or...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1961
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.25.487